Sanford-Burnham Medical Research Institute Announces Collaboration with Ortho-McNeil-Janssen Pharmaceuticals, Inc., to Discover New Medicines for Alzheimer?s Disease and Neuropsychiatric Disorders

Sanford-Burnham Medical Research Institute Announces Collaboration with Ortho-McNeil-Janssen Pharmaceuticals, Inc., to Discover New Medicines for Alzheimer?s Disease and Neuropsychiatric Disorders

Sanford-Burnham Medical Research Institute Announces Collaboration with Ortho-McNeil-Janssen Pharmaceuticals, Inc., to Discover New Medicines for Alzheimer’s Disease and Neuropsychiatric Disorders

La Jolla, Calif. (Vocus/PRWEB) January 17, 2011

Sanford-Burnham Medical Research Institute (Sanford-Burnham) has entered into a collaboration with Ortho-McNeil-Janssen Pharmaceuticals, Inc., (OMJPI) to discover compounds for Alzheimer’s disease and major psychiatric disorders. Under the agreement, multi-disciplinary teams from Sanford-Burnham and OMJPI will collaborate to identify and validate new targets for drug discovery and will seek compounds suitable for lead optimization and further development by OMJPI.

OMJPI gains exclusive access for a three-year term to a multi-disciplinary team of world-class scientists and a translational infrastructure dedicated to finding new approaches to treating patients with devastating neurological and psychiatric conditions.

For Sanford-Burnham, the collaboration with researchers at a major pharmaceutical company will help the Institute achieve its mission of translating high-impact science into important new therapies. “This represents the first of what we expect to be a series of thematic collaborations that focus our tremendous scientific and translational firepower on major unmet medical problems. Working in concert with strong partners, we can bridge the gap between early- and late-stage drug development,” said Dr. John Reed, CEO of Sanford-Burnham.

Sanford-Burnham will also receive funding including: upfront and yearly access fees, funding of discovery research in the field, milestone payments and royalties for successfully developed products. A joint steering committee will oversee the collaboration, which includes a drug discovery team funded by OMJPI in the Conrad Prebys Center for Chemical Genomics (CPCCG) at Sanford-Burnham.

CPCCG is Sanford-Burnham’s state-of-the-art screening facility established by the National Institutes of Health as part of a national effort to accelerate the rate of commercialization of basic research by generating small molecule probes that can be used to develop a pipeline of drugs to treat unmet medical needs. Sanford-Burnham’s drug discovery capabilities include: ultra high-throughput screening; high content screening; phenotypic screening; and target deconvolution technologies. CPCCG is led and staffed by industry-trained professionals who work closely with Sanford-Burnham investigators and industry collaborators to assist them in translating their scientific findings into actionable projects for new drug discovery.

“This agreement sets the stage for Sanford-Burnham to fully leverage the drug discovery infrastructure the Institute has put into place over the last five years,” said Dr. Michael Jackson, Vice President, Drug Discovery and Development at Sanford-Burnham.

Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. Recent estimates from the Alzheimer’s Association put the number of people in the U.S. with Alzheimer’s at 5.3 million. While four drugs that temporarily improve cognitive function in Alzheimer’s patients are on the market, currently, there is no treatment available to stop the progression of Alzheimer’s disease.

Major psychiatric disorders, such as bipolar disorder, major depressive disorder and schizophrenia, are a huge burden on society. These conditions have their onset in adolescence or early adulthood, and impair overall health as well as the ability to learn, work and function in society. According to the National Institute of Mental Health 2.3 million adult Americans suffer from bipolar disorder, a condition associated with profound alterations of mood. Similar to other chronic health conditions, such as diabetes or heart disease, bipolar disorder and other major psychiatric illnesses must be treated and managed throughout a person’s life.

About Sanford-Burnham Medical Research Institute

Sanford-Burnham Medical Research Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. Sanford-Burnham, with operations in California and Florida, is one of the fastest-growing research institutes in the country. The Institute ranks among the top independent research institutions nationally for NIH grant funding and among the top organizations worldwide for its research impact. From 1999 – 2009, Sanford-Burnham ranked #1 worldwide among all types of organizations in the fields of biology and biochemistry for the impact of its research publications, defined by citations per publication, according to the Institute for Scientific Information. According to government statistics, Sanford-Burnham ranks #2 nationally among all organizations in capital efficiency of generating patents, defined by the number of patents issued per grant dollars awarded.

Sanford-Burnham utilizes a unique, collaborative approach to medical research and has established major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute is especially known for its world-class capabilities in stem cell research and drug discovery technologies. Sanford-Burnham is a nonprofit public benefit corporation. For more information, please visit

Media Contacts:

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Sanford-Burnham Medical Research Institute                


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7 Replies to “Sanford-Burnham Medical Research Institute Announces Collaboration with Ortho-McNeil-Janssen Pharmaceuticals, Inc., to Discover New Medicines for Alzheimer?s Disease and Neuropsychiatric Disorders”

  1. I have so many medical bills I cannot buy anything or rent an apartment due to medical bills.
    A new kind of poor is happening. People have so many medical bills they cannot pay.
    Than the bill collectors start than the bill collectors sell the bills and than the harassment really starts. My daughter is 25 with type 1 diabetes and cannot get any help.
    If we cannot get medical care a new kind of poor is happening.
    Many people are going to on the streets due to medical bills.
    The medical industry wants everything you have.

  2. one of the “medicines” for iron deficiency is a good steak. Why is it that the good-tasting medicines are bad for you and the bad-tasting medicine is supposed to be good for you? .

    Glad to hear that things went smoothly for you during the procedure. I hope the analysis of the polyp shows that it is benign.

    (By the way, I'm having loads of fun with my new “toy”!)

  3. From the first comment on that article:I never post here, but after seeing this, I just had to.The Light article is very biased and disingenuous – they have an agenda that’s obvious from the tone of their text. For a realistic rebuttal, check out: are many other realistic, balanced rebuttals to the Light article out there as well.I’ve worked in the the biotech and drug industry (10 years) and am currently an academic. I’ve been on both sides of the fence and have a realistic perspective on how much it costs and how tough it is to discover and develop new medicines. The Light/Warburton figure is WAY off.

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